SAM-e is an amino acid derivative that has been clinically proven to benefit brain and joint function. Found in all living cells, SAM-e is also called "activated" methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM-e have indentified the following benefits of SAM-e 200:

Joint Strenght

SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e.

Brain Metabolism

SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-dopa, dopamine and related hormones, epinephrine and phosphatidylcholine (a component of Lecithin).

Longevity

Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influence longevity.

Liver

SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.

Jarrow Formulas SAM-e 400 is foil blister-packed to maximize stability and safety. Do not use if seal of blister pack is broken.

Full Potency 400 mg elemental SAM-e is defived from 800 g of tosylate disulfate SAM-e.